Corticosteroids - Buy Dexamethasone, Solu Cortef, Depo Medrol, Vetalog
Cortisol and corticosterone are the natural body corticosteroids produced by the adrenal glands. which are stimulated to produce corticosteroids by adrenocorticotropic hormone (ACTH). Release of ACTH from the pituitary gland is influenced by factors like stress, exercise, cold exposure, hypoglycemia and surgery. The major control of ACTH release is feedback inhibition by high blood levels of corticosteroids. The corticosteroids have potent anti-inflammatory activity. They stimulate the cellular production of lipocortin, which inhibits phospholipase A2, the enzyme responsible for cleaving arachadonic acid from damaged cell walls. Therefore the corticosteroids inhibit both the lipoxygenase and cyclooxygenase pathways of inflammation, blocking formation the leukotrienes as well as prostaglandins, prostacyclin, thromboxane. Some corticosteroids for veterinary use are: Hydrocortisone, Prednisone, Methylprednisone, Triamcinolone, Isoflupredone, Dexamethasone, Betamethasone, Flumethasone. |
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